(* indicating authors contributed equally, IF = Impact factor)
Shan L, among author, Balesar R, Swaab D and Lammers GJ, Fronczek R. Activated wake systems in narcolepsy type 1. Ann of Neurol. 2023 Jul 3. doi: 10.1002/ana.26736.
annals_of_neurology_-_2023_-_shan_-_activated_wake_systems_in_narcolepsy_type_1.pdf | |
File Size: | 2665 kb |
File Type: |
Seifinejad A., Neiteler A., Shan L., Sha L.,Pfister C.,Fronczek R., among author Tafti M. Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy PNAS 2023
narcolepsy_epigentic.pdf | |
File Size: | 1220 kb |
File Type: |
Shan L., Balesar R, Swaab D and Lammers GJ, Fronczek R. Reduced numbers of corticotropin-releasing hormone neurons in narcolepsy type 1. Annals of Neurology 2022
annals_of_neurology_-_2022_-_shan_-_reduced_numbers_of_corticotropin‐releasing_hormone_neurons_in_narcolepsy_type_1.pdf | |
File Size: | 1713 kb |
File Type: |
Shan, L., Swaab, D.F. Changes in histaminergic system in neuropsychiatric disorders and the potential treatment consequences. Curr. Neuropharmacol 2021
Shan, L., Martens, G.J.M., Swaab, D.F. Histamine-4 receptor: emerging target for the treatment of neurological diseases. The Current Topics in Behavioral Neuroscience 2021
Shan L, Fronczek R, Lammers GJ, Swaab DF The Tuberomamillary Nucleus in neuropsychiatric disorders Handbook of Clinical neurology Elsevier Amsterdam 2021
Fronczek R, Schinkelshoek M, Shan L, Lammers GJ. The orexin/ hypocretin system in neuropsychiatric disorders: relation to signs and symptoms Handbook of Clinical neurology Elsevier Amsterdam 2021
Shan, L., Martens, G.J.M., Swaab, D.F. Histamine-4 receptor: emerging target for the treatment of neurological diseases. The Current Topics in Behavioral Neuroscience 2021
Shan L, Fronczek R, Lammers GJ, Swaab DF The Tuberomamillary Nucleus in neuropsychiatric disorders Handbook of Clinical neurology Elsevier Amsterdam 2021
Fronczek R, Schinkelshoek M, Shan L, Lammers GJ. The orexin/ hypocretin system in neuropsychiatric disorders: relation to signs and symptoms Handbook of Clinical neurology Elsevier Amsterdam 2021
Fang, Q., Xicoy, H., Shen, J., Luchetti, S., Dai, D., Zhou, P., Qi, X.-R., Martens, G.J.M., Huitinga, I., Swaab, D.F., Liu, C.*, Shan, L.*. Histamine-4 receptor antagonist ameliorate Parkinson-like pathology in the striatum. Brain, Behavior, and Immunity 2020 Nov PMID 33249171
fang2020.pdf | |
File Size: | 4964 kb |
File Type: |
Feng CX, Bao XM, Shan L, Ling YX, Ding, Yf, Wang J, Cao YZ, Wang QW, Cui W, Xu Sj, Calcium-Sensing Receptor Mediates β-Amyloid-Induced Synaptic Formation Impairment and Cognitive Deficits via Regulation of Cytosolic Phospholipase A2/Prostaglandin E2 Metabolic Pathway Frontiers in Aging Neuroscience
Dong YT, Cao K, Xiang J, Shan L, Guan ZZ. Silent Mating-type Information regulation 2 homolog 1 attenuates the neurotoxiciy associated with Alzhemier’s disease via a mechanism which may involve regulation of peroxisome proliferator activated receptor gamma coactivator-1 a Am J Pathology 2020 Jul 190 7 1545-1564. PMID32289286
Shan L, Fronczek R, Lammers GJ, Swaab DF The Tuberomamillary Nucleus in neuropsychiatric disorders Handbook of Clinical neurology Elsevier Amsterdam 2020
Qi XR, Kamphuis W, Shan L. Astrocyte Changes in the Prefrontal Cortex From Aged Non-suicidal Depressed Patients Frontiers in Cellular Neuroscience 13 503 2019 IF 3.9
fncel-13-00503.pdf | |
File Size: | 2849 kb |
File Type: |
Zhou P, Homberg J, Fang QY, Wang Jq, Li Wz, Meng Xz, Shen Jq, Luan Y, Liao P, Swaab D, Shan L*, Liu Cq*. Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model Brain, Behavior, and Immunity Feb 2019 IF 6.3
zhoupei2018.pdf | |
File Size: | 7800 kb |
File Type: |
Thannickal TC, John J, Shan L, et al. Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy Science Translational Medicine 27 Jun 2018 IF: 17.6
eaao4953.full__1_.pdf | |
File Size: | 5363 kb |
File Type: |
Shan L et al.,Impaired fear extinction in serotonin transporter knockout rats is associated with increased 5-hydroxymethylcytosine in the amygdala" in CNS Neuroscience & Therapeutics 2018. IF:4.0
shan_et_al-2018-cns_neuroscience___therapeutics.pdf | |
File Size: | 1168 kb |
File Type: |
Ronald M, Shan L, MF Wu, and JM Siegel., Diurnal fluctuation in the number of hypocretin/orexin and histamine producing: Implication for understanding and treating neuronal loss in Plos one 2017 Jun 1;12(6):e0178573. IF: 2.8
shan2017.pdf | |
File Size: | 3276 kb |
File Type: |
Shan L, Bao AM, Swaab DF., Changes in Histidine Decarboxylase, Histamine N-Methyltransferase and Histamine Receptors in Neuropsychiatric Disorders in Handb Exp Pharmacol. 2017 Feb 24. doi: 10.1007/164_2016_125
swaab_histamine_book_chapter-2.pdf | |
File Size: | 431 kb |
File Type: |
Shan L, Dauvilliers Y, Siege J.,nteractions of the histamine and hypocretin systems in CNS disorders Nature review neurology. 2015 Jun 23. PMID: 26100750 IF: 20.5
shan_2015.pdf | |
File Size: | 1847 kb |
File Type: |
Shan L, Bao A-M, Swaab DF., The human histaminergic system in neuropsychiatric disorders. Trends in Neurosciences, 2015 Mar;38(3):167-77. PMID: 25575625 IF: 14.3
shan2015.pdf | |
File Size: | 3335 kb |
File Type: |
Shan L, Schipper P, Nonkes L. Homberg JR. Impaired fear extinction as displayed by serotonin transporter knockout rats housed in open cages is disrupted by IVC cage housing. Plos one 2014 Mar 21;9(3):e91472. PMID:24658187 IF 3.7
Shan2014plosone.pdf | |
File Size: | 381 kb |
File Type: |
Shan L, Swaab D F., Bao A-M. Neuronal histaminegic system in aging and age-related neurodegenerative disorders. Experimental gerontology. 2013 Jul;48(7):603-7. PMID:22910064 IF 3.7
exp_gerontol_shan_2013.pdf | |
File Size: | 193 kb |
File Type: |
Shan L, Qi X-R, Balesar R., Swaab D F., and Bao A-M Unchanged histaminergic system in depression: a postmortem study. Journal of Affective Disorders 2013 April 5;146(2):220-3.PMID: 23026128 IF 3.5
ShanJAD2013.pdf | |
File Size: | 171 kb |
File Type: |
Shan L, Bossers K, Unmehopa U, Bao A-M and Swaab D F.. Alterations in the histaminergic system in Alzheimer’s disease: a postmortem study. Neurobiology of Aging 2012 Nov; 33(11) 2585–2598 PMID: 22284987 IF: 6.6
nba2012shan2585.pdf | |
File Size: | 3121 kb |
File Type: |
Shan L *, Liu CQ*, van Heerikhuize J, Bao A M and Swaab D F. Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus Neurobiology of Aging. 2012 Jul;33(7):1343-4. PMID: 21371786 IF:6.6
Shanneurobiology_of_aging2012.pdf | |
File Size: | 329 kb |
File Type: |
Shan L, Bossers K, Bao A M and Swaab D F. Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson’s patients: a postmortem study. Neurobiology of Aging 2012 Jul;33(7):1488.e1-13. PMID: 22118942 IF:6.6
Shanneurobiology_of_aging2012pdsn.pdf | |
File Size: | 4435 kb |
File Type: |
Shan L, Hofman M., van Wamelen D J., Van Someren E J.W., Bao A M, and Swaab D F. Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. Sleep. 2012 May 1;35(5):713-5.PMID: 22547898 IF:5.6
sleep2012shan.pdf | |
File Size: | 617 kb |
File Type: |
van Wamelen DJ*, Shan L *, Aziz NA, Anink JJ, Bao AM, Roos RA, Swaab DF. Functional Increase of Brain histamine signaling in Huntington's disease. Brain Pathology 2011 Jul;21(4):419-27. PMID: 21106039 IF:6.1
brainpathology2010.pdf | |
File Size: | 381 kb |
File Type: |
Liu CQ *, Shan L *, Balesar R, Luchetti S, van Heerikhuize J, Luo JH, Swaab DF and Bao A-M. A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival postmortem human brain tissue. Methods. 2010 Dec;52(4):359-66. PMID: 20621191 IF: 4.5
methods2010.pdf | |
File Size: | 1807 kb |
File Type: |
Wilhelmus M. M., Verhaar R, Andringa G, Bol JG, Cras P, Shan L, Hoozemans JJ. M., Drukarch B. Presence of tissue Transglutaminase in Granular endoplasmic Reticulum is characteristic of melanized neurons in Parkinson's disease brain. Brain pathology 2011 Mar;21(2):130-9PMID:20731657 IF:6.1
shanbrainpathology2010.pdf | |
File Size: | 1377 kb |
File Type: |
Qiu S, Zhang XM, Cao JY, Yang W, Yan YG, Shan L, Zheng J, Luo JH. An endoplasmic reticulum retention signal located in the extracellular amino-terminal domain of the NR2A subunit of N-Methyl-D-aspartate receptors. J Biol Chem 2009 284(30): 20285-98 PMID: 19487695 IF: 5.3
ShanJBC2009.pdf | |
File Size: | 3542 kb |
File Type: |